Clinical Brief: The Disproportionate Burden of ATTR-CM In African Americans
ATTR cardiac amyloidosis (ATTR-CM) is a complex disease that remains challenging to diagnose and treat, and disproportionally affects African American patients. Low awareness about the disease, and limited therapeutic options are significant barriers to optimal care, however, significant advances have been made in the development of novel targeted-therapeutics that may improve patient outcomes. This clinical brief will review some of those advances in order to increase awareness about current gaps and disparities in ATTR-CM.
This activity is designed for US-based healthcare professionals, including primary care clinicians (PCPs), registered nurses, nurse practitioners (NPs), physician assistants (PAs), endocrinologists, diabetologists, pharmacists, cardiologists, lipidologists, dieticians, and other allied health professionals.
After completing this activity, the participant should be better able to:
- Define the pathophysiology, prevalence, and types of ATTR-CM.
- Recognize the disproportionate burden of ATTR-CM in African Americans and the significance of Val122l mutation.
- List current and emerging screening and diagnostic approaches aimed to optimize the early identification of African American patients with ATTR-CM.
- Review the different options for the treatment of ATTR-CM, including new and emerging novel targeted agents.
Keith C. Ferdinand, MD, FACC, FAHA, FASPC, FNLA
Gerald S. Berenson Endowed Chair in Preventive Cardiology
Professor of Medicine
John W. Deming Department of Medicine
Tulane University School of Medicine
New Orleans, LA
Dr. Ferdinand discloses the following:
- Consulting Fee (e.g., Advisory Board): Amgen, Novartis, Medtronic, Boehringer Ingelheim, Quantum Genomics, Janssen
ESTIMATED TIME TO COMPLETE ACTIVITY
EDUCATIONAL GRANT SUPPORT
This activity is supported by an educational grant from Alnylam Pharmaceuticals, Inc
JOINT PROVIDERSHIP STATEMENT
This activity is jointly provided by Global Education Group and Cardiometabolic Health Congress.
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Cardiometabolic Health Congress. Global is accredited by the ACCME to provide continuing medical education for physicians
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Global Education Group designates this continuing education activity for 0.5 contact hour(s) (0.05 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number (UAN): 0530-9999-22-206-H01-P
This is a knowledge-based activity.
DIETICIAN ACCREDITATION STATEMENT
Global Education Group is a Continuing Professional Education (CPE) Accredited Provider with the Commission on Dietetic Registration (CDR). CDR Credentialed Practitioners will receive 0.5 Continuing Professional Education units (CPEUs) for completion of this activities / materials. CPE Provider #GE012
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All relevant financial relationships have been mitigated.
The planners and managers have the following relevant financial relationships with ineligible companies:
|Name of Planner or Manager||Reported Financial Relationship|
|Rhys Williams, MSN, FNP-C, RN||Nothing to disclose.|
|Lindsay Borvansky||Nothing to disclose.|
|Andrea Funk||Nothing to disclose.|
|Liddy Knight||Nothing to disclose.|
|Ashley Cann||Nothing to disclose.|
|Karin McAdams||Nothing to disclose.|
|Shpetim Karandrea, PhD||Nothing to disclose.|
|Neha Agarwal, PhD||Nothing to disclose.|
DISCLOSURE OF UNLABELED USE
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Cardiometabolic Health Congress do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
METHOD OF PARTICIPATION & REQUEST FOR CREDIT
This activity is complimentary and available during the period September 19, 2022 through September 19, 2023. Participants must read the learning objectives and faculty disclosures, study the educational activity, obtain a score of 70% or better on the post-test, and complete the evaluation. Upon completing, your certificate will be be available for print. For questions about receiving certificates, please contact us at CMHC_Eval@cardiometabolichealth.org.
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For Pharmacists: Please complete the evaluation instructions above. Upon registering and completing the activity evaluation, your transcript information will be sent to the NABP CPE Monitor Service within 4-6 weeks.
- 0.50 ACPE Pharmacy
- 0.50 AMA PRA Category 1 Credit™
- 0.50 ANCC
- 0.50 CDE
- 0.50 Participation
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