The Gut-Skin Connection: The Microbiome and Its Effects on the Skin

**This activity has expired and is no longer eligible for CE credit. The content is still available to view.

There is no doubt that clinicians have been exposed to more information about the human gut than ever before, and most practitioners treating skin disorders have had some form of education related to the skin microbiome. However, the question remains as to how the gut microbiome affects the skin, and vice versa, the ways in which treatments for skin diseases affect the gut.  How can this new focus and insight into the gut be applied to practice?  During this engaging and interactive meeting, you will have a chance to hear from and interact with experts across specialties on what we know about the gut, how it relates to the skin and what we can do to enhance our patients’ outcomes. 

The human gastrointestinal (GI) tract harbors approximately 500 different species of microorganisms that contribute to host homeostasis, allostasis, and pathogenesis of disease. Collectively referred to as the gut microbiota, the composition of these microorganisms can be heavily influenced by intake of prebiotics, probiotics, and synbiotics. Intentional modulation of the gut microbiome has proven beneficial in the prevention and/or treatment of inflammatory skin diseases including acne vulgaris, atopic dermatitis, and psoriasis. This presents a unique opportunity for physicians to exploit the complex immune mechanisms that extend from the gut microbiome to involve distant organ systems including the skin.

This program serves to introduce healthcare practitioners to the human gut microbiome and review the ways in which it can be modified to benefit gut and skin health. Participants will gain education that allows them to better understand the gut-skin axis and explore potential therapeutic options for harnessing the gut microbiome’s influence in the treatment of skin disease.

Target Audience

This activity is designed to meet the needs of physicians, nurses and professional staff members of medical practices.

Learning Objectives

Upon completion of the educational activity, participants should be able to:

  • Review the function of the gut and the nexus of the gut microbiome and the skin
  • Discuss the role of the gut microbiota in the pathogenesis of common skin disorders
  • Interpret the roles of testing, nutrition, probiotics/prebiotics, in addressing dysbiosis of the gut microbiota
  • Apply evidence-based interventions that affect the gut microbiome in order to better treat skin disorders
Course summary
Course opens: 
Course expires: 


  • Introduction: Nexis Between the Gut and Skin - Whitney Bowe, MD; Todd LePine, MD
  • Gut Microbiome - Inflammation and GI Health
  • Introduction: General Gut Function: “The Science”  - Thomas Guilliams, PhD
  • The Gut Microbiome and Its Function - Thomas Guilliams, PhD
  • The Role of Nutrition in Gut and Skin Health: A Clinical Perspective - Todd LePine, MD
  • Foundations of the Gut Microbiome: Early Colonization of the Gut & Skin - Todd LePine, MD
  • Disturbances in the Gut: Affecting Our Skin - Whitney Bowe, MD; Todd LePine, MD
  • Skin Conditions Affected by Dysbiosis: AD, Psoriasis, Acne, Aging
  • A Dermatologist’s Perspective: Misinformation, Antibiotics, Gut-Brain-Skin Connection - Whitney Bowe, MD
  • Medical Derm: Atopic Dermatitis - Peter Lio, MD
  • Medical Derm: Acne & Rosacea - Raja Sivamani, MD
  • Medical Derm: Sensitive Skin - An Epidemic Peter Lio, MD
  • Cosmetic Derm: Age Related Changes in the Skin - Raja Sivamani, MD
  • Medical Derm: Antibiotics and Gut Health - Peter Lio, MD
  • How Do We Fix This? Testing, Nutrition, Probiotics, Prebiotics, Fiber Review
  • Are Probiotics the New Antibiotics? - Whitney Bowe, MD; Todd LePine, MD
  • Analytics and Testing of the Gut Microbiome -Todd LePine, MD
  • Live Case Presentations, How-To-Treat: Panel Discussion and Q & A

Whitney Bowe, MD (Co-Chair)

Assistant Clinical Professor

Mount Sinai Hospital

New York, NY


Todd LePine, MD (Co-Chair)

Integrative Medical Physician

Stockbridge, MA


Thomas Guilliams, PhD

Clinical Instructor

University of Wisconsin School of Pharmacy

George Washington University

Founder and Director

Point Institute

Wausau-Stevens Point, WI



Peter Lio, MD

Clinical Assistant Professor

Dermatology and Pediatrics

Northwestern University

Chicago, IL


Raja Sivamani, MD

Integrative Dermatologist

Director of Clinical Research

Zen Dermatology

Sacramento, CA


Disclosure of Conflicts of Interest

It is the policy of AKH Inc. to ensure independence, balance, objectivity, scientific rigor, and integrity in all of its continuing education activities. The author must disclose to the participants any significant relationships with ineligible companies whose products or devices may be mentioned in the activity or with the commercial supporter of this continuing education activity. Identified conflicts of interest are mitigated by AKH prior to accreditation of the activity. AKH planners and reviewers have no relevant financial relationships to disclose.

Name of Faculty or Presenter

Reported Financial Relationship

Whitney Bowe, MD

Nothing to disclose

Thomas Guilliams, PhD

Consultant: Ortho Molecular Products

Todd LePine, MDScientific Advisory Board: Diagnostic Solutions Laboratory

Peter Lio, MD

Consultant: Almirall, ASLAN Pharmaceuticals, UCB, Dermavant, Regeneron/Sanofi Genzyme, Pfizer, LEO Pharmaceuticals, AbbVie, Eli Lilly, Micreos, L'Oreal, Pierre-Fabre, Johnson & Johnson, Level ex, Unilever, Menlo Therapeutics, Theraplex, IntraDerm, Exeltis, AOBiome, Realm Therapeutics, Altus Labs, Galderma, Verrica, Arbonne, Amyris, Bodewell, YobeeCare, Burt's Bees, My-Or Diagnostics, and Kimberly Clark

Contracted Research: AbbVie, Regeneron/Sanofi, AOBiome

Royalties: Theraplex AIM OTC moisturizer

Speakers Bureaus: Regeneron/Sanofi Genzyme, Pfizer, LEO Pharmaceuticals, Eli Lilly, Galderma, and L'Oreal

Stock: Altus Labs, MIcreos, YoBeeCare

Raja Sivamani, MD

Consultant: Burt's Bees, Novozymes, Nutrafol, AbbVie, Leo Pharmaceuticals, UCB, Sun and Regeneron Pharmaceuticals

Scientific Advisor: Arbonne


Dorothy Caputo, MA, BSN, RN - AKH CE Director of Accreditations, has nothing to disclose.

AKH Planners and Reviewers have no relationships to disclose.

The content manager, Amy Kousouros, from LivDerm, has nothing to disclose.

All of the relevant financial relationships listed for these individuals have been mitigated.



**This activity has expired and is no longer eligible for CE credit.



Jointly provided by the AKH Inc., Advancing Knowledge in Healthcare and Tarsus Cardio Inc. dba LivDerm

Estimated time to complete activity: 3 hours

Commercial Support
There is no commercial support for this activity.

Physician Continuing Medical Education

Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by AKH Inc., Advancing Knowledge in Healthcare and Tarsus Cardio dba LiVDerm. AKH Inc., Advancing Knowledge in Healthcare is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

AKH Inc., Advancing Knowledge in Healthcare designates this enduring material for a maximum of 3.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Credit being awarded: 3.0 ANCC contact hours


This course is designed solely to provide the healthcare professional with information to assist in his/her practice and professional development and is not to be considered a diagnostic tool to replace professional advice or treatment. The course serves as a general guide to the healthcare professional, and therefore, cannot be considered as giving legal, nursing, medical, or other professional advice in specific cases. AKH Inc. specifically disclaim responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through participant's misunderstanding of the content.

Disclosure of Unlabeled Use and Investigational Product

This educational activity may include discussion of uses of agents that are investigational and/or unapproved by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


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