Chronic pelvic pain (CPP) in women is highly prevalent yet too often approached solely as a gynecological issue and with standard treatments such as surgery and hormones. Unfortunately, CPP often persists despite multimodal treatment. This session will describe the impact and significance of pelvic floor myofascial pain in the context of CPP. Anatomical, biomechanical, and visceral influences in the etiology of pelvic floor myofascial pain will be discussed along with central sensitization. Attendees will be educated on the appropriate clinical physical examination in this population along with evidence-based diagnostics and up-to-date treatment options focused on pelvic floor myofascial pain.