Opioids are an essential component of treating moderate to severe pain in patients with serious or advanced illness. In this presentation learners will understand opioid nomenclature, and the pharmacologic differences between opioids. The appropriate use of opioids in palliative care, and specific pain syndromes will be addressed. Participants will also learn about opioid-related adverse effects and management of such. This session will also address opioid myths and misconceptions and address how to dispel these misunderstandings with patients, families and other healthcare providers.