Music therapy’s integrative role in breathing capacity and sleep is influencing health and wellness outcomes. The use of music visualization and entrainment provides a host of strategies that can be implemented in the treatment of chronic diseases. Assessment of stress and anxiety can overwhelm the body, impeding sleep and dysregulating activities of daily living. This presentation will include research and clinical findings from the Louis Armstrong Center for Music and Medicine inclusive of music’s clinical impact affecting breathing, quality of life, sleep, and anxiety in children and adults, whose enhanced potential of control and management of symptomatology increases resilience and well-being with improved sleep.