This session is designed to familiarize attendees with what osteopathic manipulative treatment entails, its underlying models, indications, and how the procedure is performed, as well as how OMT fits into the pantheon of treatment options and when to consider it. Applications to different clinical issues and research will be reviewed. Real-world examples of usage will be provided, drawing from clinical experience and cases to illustrate underlying principles, along with a review of relevant research as it relates to these examples.