This comprehensive course dives deep into the significant impact of migraine on both individual lives and broader societal frameworks. By exploring the condition's extensive effects on quality of life, health outcomes, and economic stability, participants will be equipped with a profound understanding of how migraines influence various aspects of daily living and societal functioning. The course begins by examining the health-related quality of life for individuals suffering from migraines, detailing how these chronic conditions affect activities of daily living, as well as social and family life. Discussions will also cover the economic burden of migraines, highlighting both direct medical costs and indirect costs such as lost productivity and decreased work capability. Further, the course explores the complex interplay between migraines and comorbidities. Participants will learn about the influence of additional health problems on the progression of migraines, risks associated with medication overuse, and the challenges presented by the onset of new types of migraines in patients with existing conditions. Special attention is given to the disparities in migraine diagnosis, treatment, and outcomes among different racial and ethnic groups. The course delves into why these disparities exist and how they can be addressed to provide equitable health care. Participants will also explore current and emerging therapies and learn how to individualize treatment plans based on patient-specific factors, aiming to improve overall patient care and outcomes.