Traumatic events often have adverse influences on physical and mental health and attitudes towards medical care. The term “trauma informed care” is used when every part of service is assessed and potentially modified to include a basic understanding of how trauma impacts the life of an individual seeking care. Due to the prevalence of traumatic experiences, screening for mental health and trauma is vital when assessing chronic pelvic pain (CPP) patients. CPP is a prevalent gynecologic disorder that significantly impairs women’s health and quality of life. It’s defined as persistent, noncyclic pain lasting >6 months in structures related to the pelvis. Risk factors associated with CPP include smoking, drug or alcohol abuse, heavy menstrual flow, pelvic inflammatory disease, psychological conditions like depression and anxiety, and history of trauma such as sexual abuse. The initial patient encounter is paramount to setting the stage for acquiring the chronology of a patient’s pain through screening, history, and physical exam findings. The biopsychosocial model is an ideal framework for conceptualizing differences in pain because it considers that pain is influenced by complex and dynamic interactions between multiple biological, psychological, and social factors. These patients are best served with a multimodal treatment approach that addresses both pharmacologic and nonpharmacologic options with coordination of primary care or psychiatric colleagues.