This session will discuss the use of cannabinoids in the treatment of epilepsy. Epilepsy is a heterogeneous illness with a complex neuropsychiatric symptom profile; symptoms range from temporary confusion or a staring spell to uncontrollable jerking movements of the arms and legs to loss of consciousness or awareness. Aspects of cannabinoids may lend themselves to treat the varied symptoms that may co-occur with seizure disorders. An overview of approaches for treatment with cannabinoids will be discussed. We will also review the overlaps of neurologic and psychiatric diagnostic and treatment approaches, identifying potential treatment options for using cannabinoid-based products for epilepsy